CompletedPhase 3

Efficacy and Safety Study of Esomeprazole vs Omeprazole to Treat Acute Non-Variceal Upper Gastrointestinal Bleeding

China440 participantsStarted 2006-08

Plain-language summary

The purpose of this study is to assess the efficacy and safety of Esomeprazole and Omeprazole intravenous every 12 hours for 5 days in subjects with acute non-variceal upper gastrointestinal bleeding

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Male or female aged 18-65 years. * GI bleeding or with such signs within 48 hours as judged by the investigator as to have non-variceal upper GI bleeding. * One endoscopically confirmed bleeding peptic ulcer or erosive gastritis Exclusion Criteria: * GI bleeding caused by Esophageal varices * Mallory Weiss syndrome * Zollinger-Ellison syndrome * Suspicion of gastric malignancy at baseline endoscopy * Post-Billroth-resection * Unknown source of GI bleeding · 2.Unstable vital signs

What they're measuring

Evaluate the efficacy by assessment of proportion of subjects who present with no clinically significant bleeding after 5 days treatment

Trial details

NCT IDNCT00402259

SponsorAstraZeneca

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

View on ClinicalTrials.gov More Gastrointestinal Hemorrhage trials