Abnormalities of B Lymphocytes During Systemic Lupus (NCT00401141) | Clinical Trial Compass
CompletedNot Applicable
Abnormalities of B Lymphocytes During Systemic Lupus
France30 participantsStarted 2004-04
Plain-language summary
Previous experimental data strongly suggest that B lymphocytes have intrinsic abnormalities during lupus in mice spontaneously affected by the disease. This study tries to define these abnormalities by looking at the gene expression profile of purified B lymphocytes from patients with non active systemic lupus , compared with the gene expression profile of purified B lymphocytes from healthy donnors.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria:
* non active systemic lupus
Exclusion criteria:
* immunosuppressive drugs
* more than 10 mg of prednisone per day
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Since this trial has already been completed, would the findings about B lymphocyte abnormalities in lupus change anything about how you'd approach monitoring or treating my condition?
2This study focused on understanding how B cells behave in systemic lupus erythematosus — can you explain what role my own B cells might be playing in my lupus, and whether that's relevant to the treatment options you're considering for me?
3Since this was an observational or mechanistic study rather than a treatment trial, does the research it produced point toward any newer clinical trials or targeted therapies that might be worth exploring for my situation?
4Given that this trial is completed and listed as 'Phase NA,' meaning it wasn't testing a drug or intervention, are there active treatment trials for lupus that build on this kind of B cell research that you think would be appropriate to discuss for my case?
5Are the results from this study publicly available, and if so, would reviewing them together help us understand whether any B cell-targeted therapies — like belimumab or others — might be a good fit for managing my lupus?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.