CompletedPhase 1

Sentinel Lymph Node (SLN) Biopsy for Conjunctival/Eyelid Melanoma

United States38 participantsStarted 2000-05-30

Plain-language summary

The goal of this clinical research study is to find the sentinel lymph node (SLN) (s) and biopsy it (them) to see if the patient has small or low volume metastatic disease that would otherwise have been missed.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Participants must be 18 years of age or older.
✓. Histologically documented malignant melanoma of the conjunctiva/eyelid greater than or equal to 1 millimeter in thickness, or those less than 1 mm thick that have evidence of ulceration, mitotic figures or are Clark IV.
✓. A CXR, liver enzymes, and a head and neck computed tomography (CT) or magnetic resonance imaging (MRI) negative for evidence of metastasis.
✓. Participant must have a negative ultrasound of regional lymph nodes (i.e., within 6 weeks of study enrollment).
✓. Patient provided written informed consent. In the event that non-English speaking participants are eligible for this study, a short form (if applicable) or an ICD in their language, will be utilized and completed in accordance with the MDACC Policy for Consenting Non-English Speaking Participants.

What they're measuring

Number of Patients with Sentinel Lymph Node (SLN) Positivity in Conjunctival/eyelid Melanomas

Timeframe: 3 months

Trial details

NCT IDNCT00386906

SponsorM.D. Anderson Cancer Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-09-28

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