TerminatedNot Applicable

Acetaminophen for Fetal Tachycardia: a Randomized Pilot Trial

Stopped: Poor recruitment and lack of funding

United States13 participantsStarted 2007-07

Plain-language summary

The most common cause of fetal tachycardia is maternal fever. Fetal tachycardia often precedes the maternal fever, and fetal tachycardia confounds the interpretation of electronic fetal monitoring (EFM), increasing the rate of cesarean delivery for non-reassuring fetal status (NRFS). Our hypothesis is that treatment of fetal tachycardia with acetaminophen will significantly lower maternal body temperature and significantly lower baseline fetal heart rate (FHR). The importance is that interpretation of EFM will improve, thus allowing for a decrease in cesarean delivery for NRFS.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Term pregnancy * Singleton pregnancy * Pregnancy with cephalic presentation * Pregnancy in active phase labor * Fetal tachycardia Exclusion Criteria: * Acetaminophen allergy * Clinical chorioamnionitis * Maternal fever * Non-reassuring fetal status or fetal heart rate abnormalities requiring cesarean delivery * Previous cesarean delivery * Multifetal gestation * Breech presentation * Known fetal anomaly * Known contraindication to vaginal delivery

What they're measuring

Maternal Body Temperature 90 Minutes After Randomization

Timeframe: 90 minutes

Baseline Fetal Heart Rate (FHR) After Treatment

Timeframe: 90 minutes

Trial details

NCT IDNCT00377832

SponsorWeill Medical College of Cornell University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2010-12

Results submitted2010-12-22

View on ClinicalTrials.gov More Fever trials