Low Sodium Diet and Behavioral Intervention for Reversing Arterial Stiffening in Overweight Indiv… (NCT00366990) | Clinical Trial Compass
CompletedNot Applicable
Low Sodium Diet and Behavioral Intervention for Reversing Arterial Stiffening in Overweight Individuals
United States349 participantsStarted 2007-01
Plain-language summary
Obese individuals are at risk for developing cardiovascular disease (CVD). Increasing physical activity, losing weight, and reducing sodium intake may reverse arterial stiffness and blood vessel damage that is linked to obesity. This study will evaluate the effectiveness of a low sodium diet and a behavioral weight loss intervention in reducing arterial stiffness in overweight young adults.
Who can participate
Age range
20 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Body mass index (BMI) between 25 and 35
Exclusion Criteria:
* High blood pressure currently being treated with medication
* Blood pressure greater than or equal to 140/90 mm Hg on two consecutive study visits
* Diabetes, defined as either a fasting glucose test result of .126 or current use of hypoglycemic medications
* Currently taking hyperlipidemia medication
* Currently taking vasoactive medications
* History of known atherosclerotic disease (e.g., angina, heart attack, lower extremity arterial disease)
* Underlying inflammatory condition (e.g., systemic lupus erythematosus, rheumatoid arthritis)
* Chronic infection
* Current participation in a formal exercise or weight loss program
* Pregnant or planning to become pregnant during the study
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.