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Polyvinylpyrrolidone-Sodium Hyaluronate Gel in Reducing Pain From Oral Mucositis in Young Patients With Cancer

Ireland, United Kingdom50 participantsStarted 2005-07

Plain-language summary

RATIONALE: Polyvinylpyrrolidone-sodium hyaluronate gel may lessen the pain of oral mucositis, or mouth sores, in patients undergoing treatment for cancer. PURPOSE: This clinical trial is studying how well polyvinylpyrrolidone-sodium hyaluronate gel works in reducing pain from oral mucositis in young patients with cancer.

Who can participate

Age range4 Years – 19 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

DISEASE CHARACTERISTICS: * Diagnosis of cancer, including, but not limited to, the following: * Acute lymphoblastic leukemia * Acute myeloid leukemia * Brain tumor * Hodgkin's lymphoma * Non-Hodgkin's lymphoma * Sarcoma * Wilms' tumor * Neuroblastoma * Meets 1 of the following criteria: * Admitted to an in-patient unit after undergoing chemotherapy that is anticipated to cause oral mucositis * Admitted to an in-patient unit after undergoing myeloablative therapy followed by peripheral blood stem cell or bone marrow transplantation * Is experiencing oral pain due to mucositis PATIENT CHARACTERISTICS: * No known hypersensitivity to polyvinylpyrrolidone-sodium hyaluronate gel PRIOR CONCURRENT THERAPY: * See Disease Characteristics * Concurrent analgesics allowed

What they're measuring

Timing and intensity of oral pain

Duration of action of polyvinylpyrrolidone-sodium hyaluronate gel

Acceptability, effectiveness, and adherence to regimens including polyvinylpyrrolidone-sodium hyaluronate gel

Symptoms, other than pain, considered important to the pediatric population

Trial details

NCT IDNCT00349024

SponsorChildren's Cancer and Leukaemia Group

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2009-12