CompletedPhase 2

Androgen Effect on Klinefelter Syndrome Motor Outcome

United States93 participantsStarted 2006-07

Plain-language summary

The purpose of this study is to evaluate the effects of low-dose androgen on the motor and cognitive development of boys with Klinefelter syndrome.

Who can participate

Age range4 Years – 12 Years

SexMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Karyotype diagnosis of Klinefelter syndrome * Chronological age of 4-12 years * No treatment with androgen in the past year Exclusion Criteria: * Major liver, kidney or other systemic disease * Variant karyotypes including 47,XYY males * Evidence of spontaneous onset of puberty, defined as testicular size \> 4ml

What they're measuring

Motor Function/Strength

Timeframe: 2 years per subject

Trial details

NCT IDNCT00348946

SponsorThomas Jefferson University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-11-30

Results submitted2021-05-07

View on ClinicalTrials.gov More Klinefelter Syndrome trials