UnknownNot Applicable

3D-Conformal Radiation vs Helical Tomotherapy in Prostate Cancer

Canada72 participantsStarted 2005-03

Plain-language summary

In this study we are comparing two forms of radiotherapy. This study is being done because it is not clear at present time whether intensity modulated radiotherapy (IMRT) can reduce side effects of radiotherapy compared to standard radiotherapy (called 3D-Conformal Radiotherapy).

Who can participate

Age range18 Years

SexMALE

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Inclusion criteria

✓. A pathologic diagnosis of adenocarcinoma of the prostate
✓. Age greater than 18 years
✓. ECOG performance status of 2 or less.
✓. Presence of any of the following high risk features:

Exclusion criteria

✕. Patients with contraindication to radical radiation therapy including inflammatory bowel disease
✕. Prior or active malignancy except non-melanoma skin carcinoma within 5 years of the diagnosis of prostate cancer
✕. Prior pelvic radiotherapy for other malignancies
✕. Prior cytotoxic chemotherapy
✕. Prior orchiectomy, radical prostatectomy, cryotherapy or thermal ablation therapy for prostate cancer

What they're measuring

Late rectal toxicity from radiotherapy of the prostate

Timeframe: Month 1, 4, 8, every 4 months during year 1-2, then every 6 months during years 2-5, then every 12 months until disease progression

Trial details

NCT IDNCT00326638

SponsorOttawa Hospital Research Institute

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-01

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