TerminatedPhase 4

Pregabalin for Abdominal Pain From Adhesions

Stopped: Study was terminated by the sponsor due to low accrual.

United States18 participantsStarted 2006-03

Plain-language summary

The purpose of this study is to evaluate if pregabalin demonstrates significant reduction in abdominal pain from adhesions.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Must have history of prior surgery and documented adhesions during laparoscopy or open laparotomy within 5 years * Must have undergone an evaluation to exclude other causes of abdominal pain * Abdominal pain must be present for greater than three months duration Exclusion Criteria: * Patients that are pregnant or breast feeding * Prior treatment with gabapentin, pregabalin or demonstrated sensitivity to these drugs * Patients who are immunocompromised * Patients with significant hepatic or renal insufficiency, or any significant hematologic disorder * History of illicit alcohol or drug abuse within one year * Documented serious or unstable medical or psychological condition * Malignancy within the past 5 years other than in situ squamous cell carcinoma of the skin

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Absolute Adhesional Abdominal Pain Score Assessed at Baseline Through Week 12 in Patients Treated With Pregabalin 150-300 mg Daily Compared With Patients Given Look Alike Placebo

Timeframe: Baseline and week 2 through week 12

Trial details

NCT IDNCT00310765

SponsorHenry Ford Health System

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2008-08

Results submitted2023-04-09

View on ClinicalTrials.gov More Abdominal Pain trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.