An Assessment of P-15 Bone Putty in Anterior Cervical Fusion With Instrumentation

Inclusion Criteria: * Age between 18 and 65 * Radiographically determined discogenic origin to include at least one of the following characteristics: degenerated/dark disc on MRI, decreased disc height compared to adjacent levels on radiographic film, CT, or MRI and disc herniation on CT or MRI * Radicular symptoms by history and physical exam to include at least the following characteristics: Arm/shoulder pain, decreased flexes, decreased strength and abnormal sensation * Pain level arm/shoulder \>4 on 0-10 VAS * Pain level neck \>4 on 0-10 VAS * Neck disability Index \>30 * Involved discs between C3 and C7 * Undergoing anterior cervical fusion at a single level * Failed to gain adequate relief from non-operative treatment * Able and willing to give consent to participate in study * Understand and read English at elementary level Exclusion Criteria: Systemic infection such as AIDS, HIV, and active hepatitis; Significant metabolic disease that in the surgeon's opinion might compromise bone growth such as osteoporosis or osteomalacia; Taking medication for the prevention of osteoporosis; Circulatory, cardiac, or pulmonary problems that could cause excessive surgical risk; Active malignancy; Nondiscogenic source of symptoms (e.g., tumor, etc.); Multiple level symptomatic degenerative disc disease; Previous cervical fusion; Previous cervical decompression at the same level; Acute cervical trauma or instability (i.e., subluxation \> 3 mm on flexion/extension radiographic film)…