TerminatedPhase 4

The Efficacy of Crotaline Fab Antivenom for Copperhead Snake Envenomations

Stopped: Study terminated due to declining enrollment; data analysis proceeding.

United States13 participantsStarted 2005-04

Plain-language summary

Most patients bitten by copperhead snakes do not currently receive antivenom. Some snakebite victims have long term problems with the function of the limb that was bitten. This study will determine whether early administration of antivenom to patients with mild to moderate copperhead snakebites reduces long-term complications.

Who can participate

Age range12 Months

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Envenomation by copperhead snake (Agkistrodon contortrix) within 6 hours * Mild or moderate severity envenomation Exclusion Criteria: * Allergy to antivenom or components * Severe envenomation (hypotension, severe swelling, compartment syndrome, bleeding, etc.) * Uncertain snake ID * Prior treatment with antivenom

What they're measuring

Limb Function: AMA Disability Rating Score of Envenomated Limb

Timeframe: 14 days

Limb Function: AAOS Normative Outcome Study Scoring for Envenomated Limb

Timeframe: 14 days

Limb Function: AAOS Normative Outcome Study Scoring for Envenomated Limb

Timeframe: One year

Limb Function: AAOS--time to Return to Normal Value

Timeframe: 14 days

Trial details

NCT IDNCT00303303

SponsorWake Forest University Health Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2008-05

Results submitted2012-02-09

View on ClinicalTrials.gov More Snake Envenomation trials