CompletedPhase 2

Repeat Nasal Allergen Challenge

United Kingdom22 participantsStarted 2006-02

Plain-language summary

This is a non-drug, biomarker study to assess the utility of the model of repeated nasal allergen challenges in subjects with atopic rhinitis as a method of inducing an increased response to inhaled allergen, which will more closely resemble the responses seen during the hayfever season.

Who can participate

Age range18 Years – 40 Years

SexALL

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Inclusion criteria

✓. Male and female subjects with a history of seasonal (intermittent) atopic rhinitis, aged 18-40 years.
✓. Otherwise healthy with no health problems that may jeopardize the subjects participating in the study, absence of history of other significant allergies.

Exclusion criteria

✕. Smokers (use of tobacco products in the previous 3 months).
✕. Presence of any respiratory disease other than a history of mild stable asthma not requiring treatment and associated with normal lung function (FEV1 \> 80% predicted at screening).

Trial details

NCT IDNCT00290368

SponsorImperial College London

Sponsor typeOTHER

Study typeINTERVENTIONAL

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