CompletedNot Applicable

TEDDY - The Environmental Determinants of Diabetes in the Young

United States, Finland8,667 participantsStarted 2004-09-01

Plain-language summary

The long-term goal of the TEDDY study is the identification of infectious agents, dietary factors, or other environmental agents, including psychosocial factors which trigger T1DM in genetically susceptible individuals or which protect against the disease. Identification of such factors will lead to a better understanding of disease pathogenesis and result in new strategies to prevent, delay or reverse T1DM.

Who can participate

Age range0 Months – 4 Months

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Newborns with high risk HLA in the general population or having a first- degree relative affected with T1DM * Newborns are less than 4 months of age Exclusion Criteria: * Have an illness or birth defect that precludes long-term follow-up or involves use of treatment that may alter the natural history of diabetes (e.g. steroids or insulin) * Refuses to have blood and stool samples stored at the NIDDK Repository

What they're measuring

Appearance of one or more islet cell autoantibodies: GADA, IAA, or IA-2A confirmed at two consecutive visits.

Timeframe: September 2025

Trial details

NCT IDNCT00279318

SponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sponsor typeNIH

Study typeOBSERVATIONAL

Primary completion2025-06-30

View on ClinicalTrials.gov More Type 1 Diabetes Mellitus trials