Active — Not RecruitingPhase 1/2

Treatment of Orthostatic Intolerance

United States150 participantsStarted 1997-04

Plain-language summary

This trial is designed to study the effects of various mechanistically unique medications in controlling excessive increases in heart rate with standing and in improving the symptoms of orthostatic intolerance in patients with this disorder.

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Chronic symptoms (\> 6 months) with standing upright Exclusion Criteria: * Obvious cause of hypovolemia or drugs that could worsen tachycardia * Chronic severe medical conditions such as cancer or ischemic heart disease

What they're measuring

Increase in heart rate with standing

Timeframe: 1-4 hours

Trial details

NCT IDNCT00262470

SponsorSatish R. Raj

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-12

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