Psychiatric Correlates of Psychogenic Movement Disorder and Non-Epileptic Seizure (NCT00255411) | Clinical Trial Compass
CompletedNot Applicable
Psychiatric Correlates of Psychogenic Movement Disorder and Non-Epileptic Seizure
United States190 participantsStarted 2005-11-09
Plain-language summary
This study will explore how the mind and the brain work to cause movement symptoms or seizures in people who do not have a recognized neurological or medical disorder. The study includes a check for psychiatric disorders, symptoms and their severity; psychiatric and personality questionnaires; and neuropsychological testing.
Normal, healthy volunteers, people who have movement symptoms not due to a brain or medical disorder and people who have seizures not due to epilepsy may be eligible for this study. All candidates must be 18 years of age or older.
All participants have a medical history, physical examination and psychological evaluation, including completion of questionnaires. People with movement symptoms or seizures have a symptoms evaluation.
Some participants also undergo neuropsychological testing, including questionnaires, pen-and-paper or computerized tests, and motor tasks.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
* INCLUSION CRITERIA:
Patients for dissociation study:
* Diagnosis of clinically definite PMD utilizing Fahn and Williams criteria. The diagnosis will be made by a movement disorders neurologist.
* Or a diagnosis of NES based on video-EEG. The diagnosis will be made by an epileptologist.
* Males or females
* Age 18 or older
* Able to provide informed consent
Patients for cognitive study:
* Diagnosis of clinically definite PMD utilizing Fahn and Williams criteria. The diagnosis will be made by a movement disorders neurologist.
* Age 18 or older
* Males or females
* Able to provide informed consent
Normal volunteers for cognitive study:
* Normal volunteers age 18 or older will be included
* Males or females
* Able to provide informed consent
EXCLUSION CRITERIA:
Patients for dissociation study:
* Diagnosis of probable or possible PMD using Fahn and Williams criteria.
* Patients with neurological disorders with elaboration of their underlying disease process including comorbid epilepsy.
* Patients with a medical condition that prevents them from taking part in the study.
* Patients with current suicidal ideation.
* Patients with a psychotic disorder.
* Patients with active substance abuse within the last 6 months.
* Patients below the age of 18.
* Patients who are not capable of consent.
* Patients with an IQ less than 55.
* Patients currently involved in lawsuits.
Patients for cognitive study:
* Diagnosis of probable or possible PMD using Fahn and Williams criteria
* …
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Trial details
NCT IDNCT00255411
SponsorNational Institute of Neurological Disorders and Stroke (NINDS)