CompletedPhase 4

Does Thinning the Blood During Surgery Prevent Blood Clots Following Total Knee Replacement Surgery

Canada30 participantsStarted 2003-07

Plain-language summary

The goal of this study is to prevent blood clots from forming during surgery and a few days after total knee replacement surgery. This study will help us identify whether using a blood thinner in the operating room will stop blood clots from forming during the operation.

Who can participate

Age range18 Years – 90 Years

SexALL

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Inclusion criteria

✓. Undergoing unilateral primary total knee arthroplasty
✓. Males and non-pregnant females ages 18-90 (pre-menopausal females will undergo a serum pregnancy test at screening)
✓. Full weight bearing status (of non-operated leg) following surgery
✓. Patient able to understand and willing to sign informed consent

What they're measuring

DVT as determined by venography

Timeframe: 5 day post op

Trial details

NCT IDNCT00253851

SponsorOttawa Hospital Research Institute

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2011-05

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