CompletedPhase 3

To Determine the Feasibility of a Clinical Trial Comparing Anticoagulants Versus Antiplatelets in the Acute Treatment of Patients With Cervical Artery Dissection

United Kingdom250 participantsStarted 2005-11

Plain-language summary

This is a feasibility study to determine if a sufficient number of patients can be recruited throughout the United Kingdom and whether sufficient endpoints can be generated for a full scale therapeutic trial of anticoagulants versus antiplatelets in acute cervical artery dissection treatment.

Who can participate

SexALL

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Inclusion criteria

✓. Extracranial carotid or vertebral artery dissection with symptom onset within the last 7 days. This includes:
✓. Ipsilateral transient ischemic attack or stroke
✓. Ipsilateral Horner's syndrome or neck pain with known date of onset.
✓. Imaging evidence of definite or probable dissection on MRI/MRA, CTA or ultrasound.

Exclusion criteria

✕. Intracranial cerebral artery dissection
✕. Symptom onset after 7 days
✕. Contraindication to either antiplatelet agents or anticoagulation therapy
✕. Patient's refusal to consent
✕. Patients who are undergoing angiography and stenting or surgery for treatment of their dissection.

Trial details

NCT IDNCT00238667

SponsorSt George's, University of London

Sponsor typeOTHER

Study typeINTERVENTIONAL

View on ClinicalTrials.gov More Cervical Artery Dissection trials