TerminatedPhase 3

Early Medical Thoracoscopy Versus Simple Chest Tube Drainage in Complicated Parapneumonic Effusion and Pleural Empyema

Stopped: insufficient enrollment

Greece, Italy, Switzerland2 participantsStarted 2005-10

Plain-language summary

Multicenter, randomized controlled study to compare early mini-invasive thoracoscopy to simple chest tube drainage in complicated parapneumonic effusions or pleural empyema. 100 patients will be recruited. Follow-up will be 3 months. It will be looked at the rate medical cure, the need for secondary interventions, death and duration of hospital stay. In a nested trial in 20 patients the intrapleural pharmacokinetics of linezolid (approved antibiotic agent) will be measured.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Septated pleural effusion (ultrasonography) in the context of a lower respiratory tract infection * Frank pleural empyema (pus) Exclusion Criteria: * Fibrothorax * Tuberculous empyema * Medical thoracoscopy cannot be performed within 24 hours * Pregnancy * Inability to give informed consent

What they're measuring

Medical cure without secondary Intervention

Death

Trial details

NCT IDNCT00234208

SponsorUniversity Hospital, Basel, Switzerland

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2007-01

View on ClinicalTrials.gov More Complicated Parapneumonic Effusion trials