CompletedPhase 2

Comparing Different Ways of Delivering Humidity to Children With Croup

Canada129 participantsStarted 2001-09

Plain-language summary

Croup affects 5% of children under 6 years of age, resulting in visits to hospital Emergency Departments, and in 1% of children, hospitalization. Traditionally, the first therapy offered is humidification which can liquify airway secretions and decrease airway swelling. This study will compare the effectivenesss of 40% and 100% humidity through a specially designed machine called a nebulizer, with the usual humidity set-up (blown into the patient's face from a hose).

Who can participate

Age range3 Months – 10 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * children aged 3 months - 10 years * croup score greater than or equal to 2 after a 30 minute waiting period Exclusion Criteria: * Symptoms of croup requiring immediate intervention with nebulized epinephrine or intubation * symptoms or signs of alternative causes of stridor * inability of caregivers to understand or speak English and/or sign for informed consent * history of chronic pulmonary disease except for asthma, or co-existent systemic disease * previous history of intubation * duration of present illness \>1 week * systemic or inhaled glucocorticoids in previous 48 hours * epinephrine in previous 4 hours

What they're measuring

changes in the croup score from baseline to 30 and 60 minutes

Trial details

NCT IDNCT00230841

SponsorThe Hospital for Sick Children

Sponsor typeOTHER

Study typeINTERVENTIONAL

View on ClinicalTrials.gov More Croup trials