Comparison of Two Lower Limb Bypass Types : Prosthesis Versus Autologous Vein (NCT00221715) | Clinical Trial Compass
CompletedNot Applicable
Comparison of Two Lower Limb Bypass Types : Prosthesis Versus Autologous Vein
France100 participantsStarted 2002-07
Plain-language summary
When medical treatments fail, critical ischemia of the lower limb often leads to surgery, i.e. above knee femoro popliteal bypass. This bypass can be performed either with DACRON or PTFE prosthesis or with the autologous saphenous vein. Both technics are used but they have not been compared regarding bypass permeability and limb salvage. Thus, this study will compare the permeability rate of above knee femoro popliteal surgery whether performed with autologous vein versus prosthesis
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* lower limbs arteritis : II to IV arteritis level, above knee femoro popliteal bypass indication
* signed informed consent
Exclusion Criteria:
* no contra indication to the use of prosthesis
* Available saphenous vein
* no major trophic trouble
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial compared prosthetic bypasses to bypasses using a patient's own vein for lower limb artery problems related to arteritis or diabetes — given my specific diagnosis, which type of bypass would my doctor think is more appropriate for me, and why?
2The main thing this trial measured was whether the bypass stayed open and working after 5 years using Doppler ultrasound — what does the long-term patency data from this kind of study tell us about the realistic durability of each approach in someone with my condition?
3Since this trial is now completed, has my doctor seen or reviewed the results, and do those findings change the recommendation they would make for my treatment?
4This trial involved actual surgery to reroute blood flow around blocked arteries — before considering a bypass, are there less invasive options like angioplasty or stenting that might be worth trying first given where I am in my condition?
5For someone managing diabetes or arteritis, how does the choice between a vein graft and a synthetic graft affect the risk of complications like infection or graft failure, based on what studies like this one have shown?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Bypass permeability 5 years after surgery, assessed trough Doppler ultrasonography