A Study of AQUAVAN® Injection Versus Midazolam HCl for Sedation in Patients Undergoing Elective Colonoscopy

Inclusion Criteria: * Patient provided a signed/dated Informed Consent and HIPAA authorization after receiving a full explanation of the extent and nature of the study; * Patient, if female, were surgically sterile, postmenopausal or non-pregnant and non lactating using an acceptable method of birth control for at least 1 month prior to dosing, with a negative urine pregnancy test result at screening and predose periods; and * Patient met American Society of Anesthesiologists (ASA) Physical Status Classification System of I to III. Exclusion Criteria: * Patient had a history of allergic reaction or hypersensitivity to any anesthetic agent, narcotic, or benzodiazepine; * Patient did not meet nils per os (NPO) status per ASA Guideline or institution's guideline. * Patient had condition(s) that, in the opinion of the Investigator, could interfere with appropriate airway management; * Patient participated in an investigational drug study within 1 month prior to study start; * Patient had a history of mental or visual impairment that would not permit successful measurement of cognitive evaluations; * Patient was unwilling to adhere to pre- and postprocedural instructions; or * Patient for whom the use of fentanyl or midazolam was contraindicated.