CompletedPhase 2

Post-nasal Drainage as an Extraesophageal Manifestation of Reflux

United States50 participantsStarted 2002-06

Plain-language summary

Objectives of this study are: * To quantitatively evaluate the relationship between extraesophageal manifestations of gastroesophageal reflux (EER) and postnasal drainage(PND)in a group of patients without radiographic or endoscopic evidence of sinonasal inflammatory disease. * To assess the efficacy of BID proton pump inhibitors (PPI) in the management of patients with symptomatic postnasal drainage.

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age \>18 and \<70; * PND as chief complaint; * No known acute or chronic sinus disease; * Nonsmokers; * Subjects with no history of esophageal or gastric surgery * Subjects with no history of allergic disease * Women non pregnant. Exclusion Criteria: * Age , 18 or \> 70; * No PND as chief complaint * Al;ergic disease or acute or chronic sinus disease; * Smokers; * Pregnant women; * Subjects with history of esophageal or gastric surgery

What they're measuring

- VAS1:Visual Analog Scale indicating severity of PND

- VAS2:Visual Analog Scale indicating frequency of PND

- VAS3:Visual Analog Scale indicating frequency of throat-clearing.

Trial details

NCT IDNCT00199953

SponsorMedical College of Wisconsin

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2007-12

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