TerminatedPhase 4

CORE: Study to Evaluate the Conducted AF-Response-Algorithm in Patients Suffering From Heart Failure and Atrial Fibrillation

Stopped: Ventricular rate during AF in CRT-patients much lower than expected

Germany100 participantsStarted 2003-12

Plain-language summary

The Medtronic InSync III Marquis Cardiac Resynchronization Therapy Defibrillator (CRT-D)-System (implantable cardioverter-defibrillator with biventricular stimulation for cardiac resynchronization) is equipped with the "Conducted-Atrial Fibrillation (AF)-Response-Algorithm (CAFR)". This algorithm is designed to maximize biventricular stimulation and thus the amount of cardiac resynchronization when atrial fibrillation occurs. The goal of the study is the evaluation of the effect of the CAFR in CRT-patients suffering from atrial fibrillation by quantification of the increase of biventricular pacing during atrial fibrillation caused by CAFR as well as the influence of the CAFR on the ventricular heart rate.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Implant of a Medtronic InSync III Marquis (7279) or later system with Conducted AF-Response Exclusion Criteria: * Medical reasons that are adverse to participation in the study and compliance by the patient * Patients who are enrolled in another study or plan to be enrolled into another study * Pregnant patients or patients who are possibly pregnant due to an unreliable form of contraception

What they're measuring

Amount of biventricular pacing in ON-group compared to OFF-group

Timeframe: 1 month post-implant to 12 months post-implant

Trial details

NCT IDNCT00170313

SponsorMedtronic Cardiac Rhythm and Heart Failure

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

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