CompletedNot Applicable

Medication-overuse Headache (MOH): Withdrawal or Use of Preventative Medications Directly?

Norway64 participantsStarted 2004-01

Plain-language summary

It is a common belief that patients with MOH rarely respond of preventative medications whilst overusing acute medications. However, no randomized trial has been done previously to prove such statement. Based on some clinical experiences, our hypothesis are patients with probably MOH may benefit from use of preventive medications better than treatment with abrupt withdrawal or no specific treatment.

Who can participate

Age range18 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * fulfill 8.2.7 probably medication-overuse headache according to the International Classification of Headache Disorders, 2th Edition (2004) Exclusion Criteria: * No benefit of all available preventative medications * no benefit of abrupt withdrawal lasting more than 3 weeks of acute medication that has been overused * cluster headache * chronic paroxysmal hemicrania * hemicrania continua, pregnancy * use of pain killers for other reasons than headache * other reasons for chronic daily headache than medication-overuse

What they're measuring

Headache Days

Timeframe: 5 month

Trial details

NCT IDNCT00159588

SponsorNorwegian University of Science and Technology

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2006-11

Results submitted2021-10-26

View on ClinicalTrials.gov More Headache trials