Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn

Inclusion Criteria: * Pregnant * Plan to deliver at Chris Hani Baragwanath Hospital or one of its satellite clinics * Plan to remain in Soweto for at least two months after delivery * Are able to understand and give informed consent * Are at least 15 years old at time of registration Exclusion Criteria: * Planned delivery by caesarean section * Antenatal ultrasound revealing major fetal congenital anomalies * Have known or suspected condition in which vaginal exams are contraindicated, e.g. placenta previa * Have a history of allergic reaction to any topical antiseptic solution * Present to labour ward with infant born before arrival * Present to labour ward with significant vaginal bleeding during labour * Present with known intrauterine fetal death prior to randomization * Subject noted to be in full cervical dilatation or have baby's head on perineum * Infant noted to be in face presentation on first vaginal examination * Noted to have genital ulcers present on first vaginal examination