Effects of Ezetimibe With Simvastatin in the Therapy of Adolescents With HeFH (Study P02579)

Inclusion Criteria: * Adolescent (ages 10 - 17 years) boys or girls weighing at least 88 lbs (40 kg). * Subjects must have high cholesterol (low density lipoprotein cholesterol \[LDL-C\] more than 159 mg/dL or 4.1 mmol/L) and a family history of high cholesterol. Exclusion Criteria: * Subjects diagnosed with delayed puberty. * Subjects who are sensitive to simvastatin and/or ezetimibe. * Subjects who drink alcohol excessively or who have a history of alcohol or drug abuse within the past 2 years. * Subjects who are known to be HIV positive, are undergoing LDL apheresis or plasma apheresis, or have had a partial ileal bypass.