HOME Study (Health Outcomes and Measures of the Environment Study) (NCT00129324) | Clinical Trial Compass
CompletedNot Applicable
HOME Study (Health Outcomes and Measures of the Environment Study)
United States468 participantsStarted 2003-03
Plain-language summary
The goal of the HOME Study is to quantify the impact of low-level fetal and early childhood exposures to environmental toxicants including lead, mercury, and other metals, pesticides, polychlorinated biphenyls (PCBs), persistent organic pollutants (PBDEs/PFCs), phthalates, phenols, environmental tobacco smoke, and alcohol on child development, neurobehavior, health, and growth. The HOME Study will also evaluate meconium as a biomarker for fetal exposure and test the effectiveness of home repairs to control lead hazards and injuries in early childhood.
Who can participate
Age range
18 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Pregnancy
* Participating prenatal practice/clinic
* Participating hospital
Exclusion Criteria:
* Residence outside study area
* Plans to move outside study area within 1 year
* Home built after 1978
* Less than 18 years of age
* Beyond 19 weeks of gestation
* Diagnosis of diabetes
* Diagnosis of seizure disorder (taking anti-seizure medication)
* Diagnosis of thyroid disorder
* Diagnosis of AIDS or positive HIV test
* Diagnosis of bipolar disorder
* Diagnosis of schizophrenia
* Diagnosis of cancer resulting in radiation treatment or chemotherapy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Lead reduction intervention, blood lead concentrations & neurobehavioral outcomes
Timeframe: 16wk & 26wk gestation, birth, annually at 1y-12y
2
Exposure to environmental chemicals and their effects on child health, neurobehavior and development