Study of Colchicine to Treat Acute Pericarditis and Prevent Recurrences (NCT00128453) | Clinical Trial Compass
CompletedPhase 3
Study of Colchicine to Treat Acute Pericarditis and Prevent Recurrences
Italy240 participantsStarted 2005-08
Plain-language summary
The purpose of the study is to determine whether colchicine is safe and effective in the treatment of acute pericarditis and the prevention of subsequent recurrences.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients with acute pericarditis (index attack)
* Age≥ 18 years
* Informed consent
Exclusion Criteria:
* Suspected neoplastic, tuberculous, or purulent etiology
* Known severe liver disease and/or elevated transaminases \>1.5 times the upper limit of normality
* Serum creatinine \>2.5 mg/dl
* Serum creatine kinase (CK) over the upper limit of normality or known myopathy
* Known gastrointestinal or blood disease
* Pregnant or lactating women or women not protected by a contraception method
* Known hypersensibility to colchicine
* Treatment with colchicine at enrolment