CompletedPhase 4

Combined Vi Vaccination and Health Education Program on the Burden of Typhoid in Childhood

Pakistan27,231 participantsStarted 2001-10

Plain-language summary

This study is part of the International Vaccine Institute's (IVI's) typhoid Vi demonstration project that aims to accelerate the rational introduction of Vi vaccines in typhoid endemic countries. The purpose of this study is to determine the effectiveness of the Vi vaccine following a mass typhoid immunization campaign in an endemic area in Karachi, Pakistan. The cost-effectiveness of Vi vaccination and the logistic feasibility of a mass typhoid immunization campaign will also be evaluated.

Who can participate

Age range2 Years – 16 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Registered in the project census * Age: 2-16 years Exclusion Criteria: * Fever \>37.5 degrees Celsius, axillary * Pregnancy * Lactating

What they're measuring

Total protection against S. typhi

Timeframe: 2 years from zero time

Trial details

NCT IDNCT00125047

SponsorInternational Vaccine Institute

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2007-08

View on ClinicalTrials.gov More Typhoid trials