Surgical Treatments Outcomes Project for Dysfunctional Uterine Bleeding (STOP-DUB)

Inclusion Criteria: * Abnormal uterine bleeding in the absence of structural pathology, pharmacologic agents, IUD use, or systemic disorders of hemostasis that could explain the condition. Exclusion Criteria: Prescreen * Age \< 18 years * Postmenopausal status (or bilateral oophorectomy) * Bleeding not considered excessive by woman * Desire to retain fertility * Refusal to consider surgery * Known myoma (from prior examination) Eligibility Screen * Lack of willingness to have a gynecologic or ultrasound examination * Lack of willingness to be interviewed about bleeding or consider study * Pregnancy * Prior endometrial resection or ablation * Prior myomectomy, myolysis, or hysterectomy Medical History * No tentative diagnosis of DUB * History of malignancy of vagina, cervix, endometrium, or ovary * History of complex endometrial hyperplasia or simple hyperplasia with atypia * Current use of tamoxifen * \< 6 months since onset of excessive uterine bleeding * \< 9 months since stopping the use of IUD * \< 9 months since stopping the use of implantable hormone agent * \< 18 months since stopping use of Depo-Provera * \< 6 months of anovulatory DUB after reaching euthyroid status for woman with diagnosis of hypothyroidism * \< 3 months since pathology results indicate presence of endometrial polyp Baseline Gynecologic Examination * Enlarged (\>= 14 weeks gestational age) uterus * Focal bleeding of genital, urinary, or gastrointestinal tract Ultrasound Examination * Pre…