CompletedNot Applicable

Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201

United States66 participantsStarted 2002-07

Plain-language summary

RATIONALE: Assessing the effects of methotrexate on brain function in children may improve the ability to plan treatment and decrease side effects. PURPOSE: Clinical trial to compare brain function of children who have been previously treated with methotrexate.

Who can participate

Age range1 Year – 9 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

DISEASE CHARACTERISTICS: * Previously enrolled on POG-9201 or POG-9605 * Good prognosis by NCI risk (9201 and 9605 stratum 1) * Eligible for the therapeutic study * Completed therapy by 12/31/2000 * No CNS3 at diagnosis * No relapsed disease PATIENT CHARACTERISTICS: Age: * 1 to 9 at diagnosis Performance status: * Not specified Life expectancy: * Not specified Hematopoietic: * Not specified Hepatic: * Not specified Renal: * Not specified Other: * No Down syndrome PRIOR CONCURRENT THERAPY: Biologic therapy * Not specified Chemotherapy * Not specified Endocrine therapy * Not specified Radiotherapy * Not specified Surgery * Not specified Other * See Disease Characteristics

What they're measuring

Percentage of patients with severe intelligence deficit as evidenced by either a verbal or performance IQ below 85

Timeframe: Length of study

Trial details

NCT IDNCT00028509

SponsorChildren's Oncology Group

Sponsor typeNETWORK

Study typeOBSERVATIONAL

Primary completion2011-07

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