Selected individuals suspected of having or with prior biopsy proof of malignant disease will be seen in the Urologic Oncology Branch, NCI. Blood samples may be collected at the time of the initial visit and at periodic intervals during the course of the disease. These samples will be stored in the tissue bank of the Urologic Oncology Branch. Aliquots of malignant and normal tissue will be collected at the time of surgery and stored in the tissue bank, Urologic Oncology Branch, NCI. These materials will be used in the research efforts of the Urologic Oncology Branch, NCI....
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Investigate quality of life in men who have prostate cancer.
Timeframe: on-going
Investigate molecular genetic basis of urologic malignancies
Timeframe: on-going
Investigate cellular/biochemical response to existing and novel therapeutic agents.
Timeframe: on-going
Examine protein expression and bioimmunoassays investigating potential genetic markers.
Timeframe: on-going
Determine the molecular genetic differences between normal and tumorigenic tissues.
Timeframe: on-going
Collection of benign and malignant tissue from individuals with rare inherited conditions associated with an increased risk for kidney cancer.
Timeframe: on-going
Collection of benign and malignant tissue from individuals with known or suspected cancer.
Timeframe: on-going