Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Pa… (NCT00003408) | Clinical Trial Compass
CompletedPhase 2
Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer
United States40 participantsStarted 1998-04
Plain-language summary
RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. Combining chemotherapy and peripheral stem cell transplantation with biological therapy may kill more cancer cells.
PURPOSE: Phase II trial to study the effectiveness of biological therapy with sargramostim, interleukin-2, and interferon alfa following chemotherapy and peripheral stem cell transplantation in treating patients who have cancer.
Who can participate
SexALL
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DISEASE CHARACTERISTICS:
* Diagnosis of one of the following cancers and undergoing high dose chemotherapy with autologous stem cell rescue (ASCR):
* Metastatic breast cancer
* Multiple myeloma
* Hodgkin's disease
* Recurrent or refractory low, intermediate, or high grade non-Hodgkin's lymphoma
* Acute myelogenous leukemia beyond first remission
* Acute lymphoblastic leukemia beyond first remission
* Ovarian cancer
* Refractory malignancy and measurable or evaluable disease (at time of ASCR)
* Hormone receptor status:
* Not specified
* A new classification scheme for adult non-Hodgkin's lymphoma has been adopted by PDQ. The terminology of "indolent" or "aggressive" lymphoma will replace the former terminology of "low", "intermediate", or "high" grade lymphoma. However, this protocol uses the former terminology.
PATIENT CHARACTERISTICS:
Age:
* Not specified
Menopausal status:
* Not specified
Performance status:
* Not specified
Hematopoietic:
* Not specified
Hepatic:
* Not specified
Renal:
* Not specified
PRIOR CONCURRENT THERAPY:
Biologic therapy:
* See Disease Characteristics
Chemotherapy:
* See Disease Characteristics
Endocrine therapy:
* Not specified
Radiotherapy:
* Not specified
Surgery:
* Not specified