Stenosis of Trachea

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Stenosis of Trachea trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

RecruitingPhase 1

NCT06085209

Cryospray Therapy for Benign Airway Stenosis

This is a clinical evaluation to assess the effectiveness of cryospray therapy used in addition to current standard of care endoscopic therapies in preventing s…

United States12 participantsStarted 2023-10-12

Treatment: The truFreeze Spray Cryotherapy, Ballon dilation

RecruitingNot Applicable

NCT07258784

RNA Sequencing of Discarded Tracheal Stenosis Tissue to Characterize Cellular and Molecular Pathogenesis

Benign tracheal stenosis is a rare but potentially life-threatening condition, typically resulting from fibroinflammatory scarring. It can be secondary to iatro…

United States10 participantsStarted 2025-09-11

Treatment: Biopsy or surgery

RecruitingNot Applicable

NCT06917222

Slide Tracheoplasty Versus Tracheal Resection Anastomosis in Acquired Tracheal Stenosis

Aim of the Work To compare the clinical outcomes between patients will undergo slide tracheoplasty and those will undergo tracheal resection anastomosis for acq…

Egypt30 participantsStarted 2025-05-01

Treatment: Slide tracheoplasty, Tracheal resection anastomosis

RecruitingPhase 2

NCT06761170

Spray Cryotherapy for the Management of Benign Central Airway Stenosis (Cryo-BAS)

The goal of this clinical trial is to compare spray cryotherapy plus balloon dilatation versus current standard of Care (SoC - steroid injection, radial cuts an…

United States50 participantsStarted 2025-06-02

Treatment: Spray cryo therapy, Standard of Care (SOC)

RecruitingNot Applicable

NCT05924087

Interventional Therapy of Tracheal Stenosis

After respiratory weaning, decannulation is sought. To do this, the tracheal cannula is first unblocked, so that patients no longer breathe in and out through t…

Germany250 participantsStarted 2023-06-01

All recent trials (47 shown)

TerminatedNot Applicable

NCT04719845

DilAtation Versus Endoscopic Laser Resection in Simple Benign trAcheal sTEnosis

Multicenter randomized controlled trial comparing endoscopic laser resection vs dilatation in benign tracheal stenosis.

Canada, France108 participantsStarted 2021-03-17

Treatment: Endoscopic laser resection, Dilatation

Not Yet RecruitingNot Applicable

NCT07191860

Paclitaxel-Coated Pulmonary Balloon for the Treatment of Benign Central Airway Stenosis

The OXYGEN-RCT trial is a randomized, controlled, double blinded, prospective, multi-center trial to demonstrate the safety and efficacy in adult benign central…

United States200 participantsStarted 2026-03-01

Treatment: The Airiver Pulmonary drug-coated balloon (DCB) dilation, Commercial airway balloon dilation

Stenosis of Trachea

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Cryospray Therapy for Benign Airway Stenosis

RNA Sequencing of Discarded Tracheal Stenosis Tissue to Characterize Cellular and Molecular Pathogenesis

Slide Tracheoplasty Versus Tracheal Resection Anastomosis in Acquired Tracheal Stenosis

Spray Cryotherapy for the Management of Benign Central Airway Stenosis (Cryo-BAS)

Interventional Therapy of Tracheal Stenosis

All recent trials (47 shown)

DilAtation Versus Endoscopic Laser Resection in Simple Benign trAcheal sTEnosis

Paclitaxel-Coated Pulmonary Balloon for the Treatment of Benign Central Airway Stenosis

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Cryospray Therapy for Benign Airway Stenosis

RNA Sequencing of Discarded Tracheal Stenosis Tissue to Characterize Cellular and Molecular Pathogenesis

Slide Tracheoplasty Versus Tracheal Resection Anastomosis in Acquired Tracheal Stenosis

Spray Cryotherapy for the Management of Benign Central Airway Stenosis (Cryo-BAS)

Interventional Therapy of Tracheal Stenosis

All recent trials (47 shown)

DilAtation Versus Endoscopic Laser Resection in Simple Benign trAcheal sTEnosis

Paclitaxel-Coated Pulmonary Balloon for the Treatment of Benign Central Airway Stenosis

Everolimus Trial in Laryngotracheal Stenosis

Transcriptomic Profile Changes in Benign Tracheal Stenosis: Wedge Resection vs. Radial Incision

Use of Steroid Injections to Prevent the Recurrence of Tracheal Stenosis in Idiopathic Subglottic Stenosis

Effects of Interleukin (IL)-17A Inhibition on Idiopathic Subglottic Stenosis

Coblation Assisted Dilatation Versus Modified Maddern Procedure in Subglottic and Cervical Tracheal Stenosis

Feasibility of Tracheobronchial Reconstruction Using Allogenic Aortic Patch in Children

Voice Quality Analysis of Patients With Laryngotracheal Stenosis

CT-Based Scoring System to Predict Surgical Need in Tracheal Stenosis (TSMAS Study)

Total Intravenous Anesthesia for Rigid Bronchoscopy Using Remimazolam

High-flow Nasal Oxygen During Rigid Bronchoscopy Under General Anesthesia: a Randomized Controlled Trial

Biodegradable Stents in the Management of Stenoses of the Large Airways

Relationship Between Post-Intubation Tracheal Stenosis and Covid-19

Long-term Outcomes of Post-intubation Tracheal Stenosis; 7-year Follow-up

Challenges and Management of Post-intubation Tracheal Stenosis

Azygos Vein Preservation; Its Impact on Early Outcomes After Neonatal EA/TOF Repair

Phenotypic and Genetic Assessment of Tracheal and Esophageal Birth Defects in Patients

Airway Management During Unusual Tracheal Stenosis

Treatment of Laryngotracheal Stenosis Using Mesenchymal Stem Cells