Sepsis, Endotoxemia, Immunosuppression

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Sepsis, Endotoxemia, Immunosuppression trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 4

NCT06624436

Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human Endotoxemia

The goal of this clinical trial is to investigate the immunomodulatory effects of the drugs dexamethasone, tocilizumab and anakinra in healthy male subjects age…

Netherlands52 participantsStarted 2024-10-24

Treatment: Dexamethasone, Tocilizumab

All recent trials (3 shown)

CompletedNot Applicable

NCT06801873

Determining the Fingerprint of Endotoxin Tolerance

An explorative, prospective study in 100 healthy volunteers who will be challenged with endotoxin twice to identify SNPs and transcripts that are associated wit…

Netherlands110 participantsStarted 2019-05-27

Treatment: Endotoxin (E. coli O:113, Reference Endotoxin)

CompletedNot Applicable

NCT05570643

The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor Cells

We will investigate whether human endotoxemia induces changes in human bone marrow cells and their downstream effector cells. To comprehensively investigate und…

Netherlands12 participantsStarted 2018-01-05

Treatment: LPS, Placebo