Ryanodine Receptor 1-Related Myopathy

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Ryanodine Receptor 1-Related Myopathy trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingNot Applicable

NCT06287762

A Natural History Study of RYR1-Related Disorders

Background: Congenital myopathies (CM) are genetic disorders that can cause decreased muscle tone and muscle weakness. Most CMs in the United States are relate…

United States150 participantsStarted 2025-03-11

All recent trials (3 shown)

Not Yet RecruitingNot Applicable

NCT06791369

The Prevalence of RYR1-related Disease

The skeletal muscle ryanodine receptor (RYR1) gene encodes an important calcium channel in skeletal muscle, with an important role in muscle contraction. Mutati…

United Kingdom2,000 participantsStarted 2025-02

CompletedPhase 1/2

NCT02362425

Antioxidant Therapy in RYR1-Related Congenital Myopathy

Background: \- Ryanodine receptor type 1-related myopathies (RYR1-RM) are the most common non-dystrophic muscle diseases that people are born with in the U.S.…

United States63 participantsStarted 2015-02-12

Treatment: N-acetylcysteine, Placebo