Recurrent Low Grade Astrocytoma

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Recurrent Low Grade Astrocytoma trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 1/2

NCT04923126

SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

This is an open-label, multi-center, Phase 1/2 study of the brain-penetrant MEK inhibitor, mirdametinib (PD-0325901), in patients with pediatric low-grade gliom…

United States132 participantsStarted 2021-06-21

Treatment: Mirdametinib

All recent trials (59 shown)

Active — Not RecruitingPhase 3

NCT04576117

A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurre…

This phase III trial investigates the best dose of vinblastine in combination with selumetinib and the benefit of adding vinblastine to selumetinib compared to…

United States300 participantsStarted 2021-02-16

Treatment: Biospecimen Collection, Magnetic Resonance Imaging

CompletedNot Applicable

NCT04988750

Evaluate the Safety and Preliminary Efficacy of the Combination of NaviFUS System With Re-irradiation for rGBM Patients

This is an open label, single arm, prospective, and pilot study. Eligible patients will be enrolled after acquiring the signed informed consent and then will re…

Taiwan7 participantsStarted 2021-05-23

Treatment: NaviFUS System

Recurrent Low Grade Astrocytoma

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

All recent trials (59 shown)

A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurre…

Evaluate the Safety and Preliminary Efficacy of the Combination of NaviFUS System With Re-irradiation for rGBM Patients

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

All recent trials (59 shown)

A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurre…

Evaluate the Safety and Preliminary Efficacy of the Combination of NaviFUS System With Re-irradiation for rGBM Patients

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas

Fluoroethyltyrosine for Evaluation of Intracranial Neoplasms

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Antineoplaston Therapy in Treating Children With Low-Grade Astrocytoma

Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Soli…

Low Dose Radiation Therapy for Glioblastoma Multiforme

Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma

Safety Study of Afatinib for Brain Cancer

Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas

Vaccine for Patients With Newly Diagnosed or Recurrent Low-Grade Glioma

Everolimus in Treating Patients With Recurrent Low-Grade Glioma

Photodynamic Therapy (PDT) For Recurrent High Grade Gliomas

Radiation Therapy in Treating Young Patients With Gliomas

Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors

Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas

Radiation Therapy or Combination Chemotherapy in Treating Patients With Clinically or Radiologically Progressive Low-Gra…