Recurrent Diffuse Hemispheric Glioma, H3 G34-Mutant

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Recurrent Diffuse Hemispheric Glioma, H3 G34-Mutant trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 1

NCT06914479

Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and…

This phase I trial tests the safety, side effects and best dose of AdV-HSV1-TK and AdV-Flt3L in combination with valacyclovir for the treatment of patients with…

United States11 participantsStarted 2026-06-01

Treatment: Ad-hCMV-Flt3L, Ad-hCMV-TK

All recent trials (4 shown)

SuspendedPhase 1

NCT06860594

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astr…

This phase I trial tests the safety, side effects, and best dose of triapine in combination with radiation therapy in treating patients with glioblastoma or ast…

United States30 participantsStarted 2025-07-30

Treatment: Biospecimen Collection, Computed Tomography

By InvitationPhase 1

NCT06896110

Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma

This is a single-arm open-label phase 1 dose escalation/expansion trial assessing the safety and efficacy of concurrent intrathecal azacitidine and intrathecal…

United States34 participantsStarted 2025-06-05

Treatment: Nivolumab, Azacitidine (AZA)

Recurrent Diffuse Hemispheric Glioma, H3 G34-Mutant

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and…

All recent trials (4 shown)

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astr…

Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and…

All recent trials (4 shown)

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astr…

Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma

Peptide-Pulsed Dendritic Cell Vaccination in Combination With Nivolumab and Ipilimumab for the Treatment of Recurrent an…