Pediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL)

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Pediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL) trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 3

NCT07152041

Newly-diagnosed Pediatric Ph-positive B-ALL Protocol

This prospective clinical trial evaluates the effectiveness and safety of "chemotherapy-light" regimen incorporating the third-generation TKI olverembatinib, th…

China150 participantsStarted 2025-03-28

Treatment: olverembatinib

All recent trials (8 shown)

Not Yet RecruitingPhase 1/2

NCT07387926

Safety and Efficacy of Asciminib in Pediatrics and Young Adults With Relapse/Refractory (r/r) Philadelphia Positive (Ph+…

Multi-center, open-label, single arm study of asciminib in participants aged ≥1 year to ≤30 years old with r/r Ph+ or ABL-class Ph-like ALL. This study will hav…

Location not specified50 participantsStarted 2026-03-26

Treatment: Asciminib Adult formulation, Asciminib Pediatric formulation

TerminatedPhase 1/2

NCT04501614

A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Ly…

This study is about an anticancer drug called ponatinib which is a tyrosine kinase inhibitor given with chemotherapy to children, teenagers, and young adults up…

United States11 participantsStarted 2021-02-24

Treatment:

Pediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL)

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Newly-diagnosed Pediatric Ph-positive B-ALL Protocol

All recent trials (8 shown)

Safety and Efficacy of Asciminib in Pediatrics and Young Adults With Relapse/Refractory (r/r) Philadelphia Positive (Ph+…

A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Ly…

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Newly-diagnosed Pediatric Ph-positive B-ALL Protocol

All recent trials (8 shown)

Safety and Efficacy of Asciminib in Pediatrics and Young Adults With Relapse/Refractory (r/r) Philadelphia Positive (Ph+…

A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Ly…

Pediatric-Inspired Chemotherapy Plus Tyrosine Kinase Inhibitor in Adult Philadelphia Chromosome-Positive Acute Lymphobla…

Pediatric Philadelphia Positive Acute Lymphoblastic Leukemia

A Pharmacokinetic (PK) Study of Nilotinib in Pediatric Patients With Philadelphia Chromosome-positive (Ph+) Chronic Myel…

Study of Efficacy and Safety of CTL019 in Pediatric ALL Patients

Glivec/Gleevec Pediatric (Age 1 to Less Than 4) PK Study in CML, Ph+ ALL Patients and Other Glivec/Gleevec® Indicated He…