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Pediatric Low-grade Glioma
Clinical trial pipeline · Data from ClinicalTrials.gov
See which Pediatric Low-grade Glioma trials may be worth asking aboutClinical trial pipeline · Data from ClinicalTrials.gov
See which Pediatric Low-grade Glioma trials may be worth asking aboutNorth America
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This is a 3-part open-label study (feasibility phase, treatment phase and follow-up phase) of orally administered mirdametinib in combination with intravenous v…
The objective of this Master Protocol is to evaluate the efficacy and safety of plixorafenib in participants with BRAF altered (BRAF V600E or BRAF fusions) loca…
Pediatric gliomas harboring BRAF-alterations, commonly BRAFV600 mutation or KIAA1549-BRAF fusion, are currently treated with either chemotherapy or mitogen acti…
This phase I trial studies the side effects and best dose of trametinib and everolimus in treating pediatric and young adult patients with gliomas that have com…
The purpose of this study is to see if 18F-Fluciclovine (Axumin®) is useful and safe in the management of children with Low Grade Gliomas (LGG). Imaging with 18…
This study aims to evaluate the efficacy of Laser Interstitial Thermal Therapy (LITT) in treating recurrent or progressive, low-grade gliomas (LGG) in pediatric…
This is a study to determine the safety and efficacy of the drug, mebendazole, when used in combination with standard chemotherapy drugs for the treatment of pe…
A roll-over study to assess long-term effect in pediatric patients treated with dabrafenib and/or trametinib.