Oropharyngeal Squamous Cell Carcinoma (OPSCCA)

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Oropharyngeal Squamous Cell Carcinoma (OPSCCA) trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 1

NCT06747390

Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery

Based on evidence that the local anesthetic lidocaine may have anticancer effects, this study will assess the safety and efficacy of intratumoral lidocaine inje…

United States30 participantsStarted 2025-04-23

Treatment: Lidocaine 1% Injectable Solution

All recent trials (3 shown)

Not Yet RecruitingPhase 2

NCT07418034

A Single Arm Phase II Trial in p16-positive Oropharynx Cancer of Selective Dose De-escalation of nodAl VolumEs at Minima…

Patients with human papillomavirus (HPV)-related oropharyngeal cancer generally have very good outcomes. Patients' treatment responses depend more on their indi…

Location not specified132 participantsStarted 2026-05

Treatment: Dose de-escalation to contralateral neck., Dose de-escalation to gross disease to contralateral neck

TerminatedNot Applicable

NCT01891695

OPSCC N0 Nodal Control With Reduced IMRT

The dose of radiation most commonly used to treat oropharyngeal cancer results in side effects including sores in the mouth and throat, dry mouth and thick sali…

United States1 participantsStarted 2013-10

Treatment: 39.6 Gy radiation