Organ Transplantation

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Organ Transplantation trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 38 trials

RecruitingPhase 1

NCT06997471

Phase I Trial on the Safety of Delayed Infusion of a Naïve T Cell-Depleted Hematopoietic Graft With Memory T Cells in So…

The goal of this clinical trial is to evaluate the safety and feasibility of inducing hematopoietic mixed chimerism to promote immune tolerance and potentially…

Spain10 participantsStarted 2025-06-10

Treatment: Investigational cellular therapy consisting on a HSCT using a graft enriched in CD34+, depleted of naïve T-lymphocytes and supplemented with memory lymphocytes

RecruitingNot Applicable

NCT05609123

Endothelial Glycocalyx Damage in Brain Death Organ Donors

The study aims the assessment of endothelial glycocalyx (EG) degradation in deceased organ donors. There is a lack of organs for the transplantation program. By…

Czechia100 participantsStarted 2022-01-01

Treatment: Endothelial glycocalyx damage assessment

RecruitingNot Applicable

NCT06367244

Transplant Wellness Program

Wellness is defined as the active pursuit of activities, choices and lifestyles that lead to a state of overall health. Prehabilitation, or using rehabilitation…

Canada420 participantsStarted 2023-11-16

Treatment: Transplant Wellness Program - Kidney and Liver

RecruitingPhase 2

NCT06552169

REgulatory T Cell Therapy to Achieve Immunosuppression REduction

The goal of this multi-national, multi-center, open-label, randomized Phase 2 trial is to determine the safety and efficacy of administering expanded regulatory…

United States, Taiwan34 participantsStarted 2025-06-13

Treatment: Arm 1: SOC (mTOR + CNI), Arm 2A: TRACT/MONO mTOR

RecruitingPhase 2

NCT05947071

High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients

Influenza virus is a significant pathogen in pediatric solid organ transplant (SOT) recipients. However, these individuals respond poorly to standard-dose (SD)…

United States312 participantsStarted 2024-09-26

Treatment: Standard Dose Quadrivalent Inactivated Influenza Vaccine, High Dose Quadrivalent Inactivated Influenza Vaccine

RecruitingNot Applicable

NCT01062581

University of Minnesota Transplant Registry

Under Transplant Information Services (TIS), the University of Minnesota Transplant Registry (UMTR) will serve as the repository for core research data.

United States10,000 participantsStarted 1997-03

All recent trials (100 shown)

Not Yet RecruitingPhase 4

NCT07570433

HORUS-Cytomegalovirus Open Proof-of-concept Exploratory Trial

Cytomegalovirus (CMV) remains a significant cause of morbidity and mortality following organ transplantation. Cell-mediated immunity plays a crucial role in co…

France, Spain, Switzerland100 participantsStarted 2026-04

Treatment: 50% reduction in the dose of MPA, Switch from MPA to a mammalian target of rapamycin inhibitor (mTORi), together with an adapted dose of tacrolimus

Not Yet RecruitingNot Applicable

NCT07447388

Development, Pilot Testing and Evaluation of the Effectiveness of Immunosuppressive Medication Adherence Care Bundle in…

Organ transplantation is the gold standard treatment method that increases the quality and duration of life in patients with end-stage organ failure, and one of…

Location not specified100 participantsStarted 2026-05-01

Treatment:

Organ Transplantation

Trial phase breakdown

Trial status

Actively recruiting — 38 trials

Phase I Trial on the Safety of Delayed Infusion of a Naïve T Cell-Depleted Hematopoietic Graft With Memory T Cells in So…

Endothelial Glycocalyx Damage in Brain Death Organ Donors

Transplant Wellness Program

REgulatory T Cell Therapy to Achieve Immunosuppression REduction

High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients

University of Minnesota Transplant Registry

All recent trials (100 shown)

HORUS-Cytomegalovirus Open Proof-of-concept Exploratory Trial

Development, Pilot Testing and Evaluation of the Effectiveness of Immunosuppressive Medication Adherence Care Bundle in…

Trial phase breakdown

Trial status

Actively recruiting — 38 trials

Phase I Trial on the Safety of Delayed Infusion of a Naïve T Cell-Depleted Hematopoietic Graft With Memory T Cells in So…

Endothelial Glycocalyx Damage in Brain Death Organ Donors

Transplant Wellness Program

REgulatory T Cell Therapy to Achieve Immunosuppression REduction

High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients

University of Minnesota Transplant Registry

All recent trials (100 shown)

HORUS-Cytomegalovirus Open Proof-of-concept Exploratory Trial

Development, Pilot Testing and Evaluation of the Effectiveness of Immunosuppressive Medication Adherence Care Bundle in…

Seroprevalence of Hepatitis E in People With an Organ Transplant

Immunogenicity of HPV Vaccine in Transplant Recipients.

Non-myeloablative Haploidentical HCT Study for Patients With Sickle Cell Disease, Including Compromised Organ Function

A Study to Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases

Study to Investigate the Efficacy and Safety of RP1 in Adult Patients With Organ Transplants and Advanced Skin Malignanc…

BZLF1 Peptide Vaccine (OSU-2131) With QS-21 for the Prevention of Epstein-Barr Virus Related Cancer in Patients Awaiting…

Belimumab to Mobilise Memory B-cells From Secondary Lymhoid Organs to Improve Memory B-cell HLA-specificity Profiling to…

Evaluating Immune Response to COVID-19 Vaccines in Patients With Cancer, Transplant or Cellular Therapy Recipients

Shared Decision Making for Kidney Transplant Candidates to Plan for an Organ Offer Decision

The Anticipated Organ Donation Approach

Pacing In Organ Donors (the POD Trial)

A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Transplant Recipients

"IL-1β Blockade to Prevent Immunothrombosis in Recipients of a Pancreatic Organ"

CMV T Cell Immunity in Pediatric Solid Organ Transplant Recipients

Recombinant Zoster Vaccine in Young Adult Solid Organ Transplant Recipients

Multicenter Study on Organ Acquisition Costs in the Post Re-Allocation Era: Liver Transplantation

Renal Ex Vivo SYN002 Perfusion to Eliminate CMV Transmission

10°C vs 4°C Lung Preservation RCT