Opioid Toxicity

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Opioid Toxicity trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 1

NCT05603702

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis

The investigators propose to conduct a dose-escalation trial of an FDA-approved antiepileptic drug, lacosamide, added to opioid therapy in patients with chronic…

United States24 participantsStarted 2023-03-17

Treatment: Lacosamide

All recent trials (7 shown)

CompletedPhase 2/3

NCT05391555

Pupillary Unrest as an Indicator of Central Opioid Effect in Subjects 40-60 Years of Age

This study will establish the relationship between magnitude of opioid exposure and a pupillary measure referred to as PUAL (pupillary unrest in ambient light),…

United States10 participantsStarted 2022-10-01

Treatment: Remifentanil Hydrochloride, Pupillometry measurement

CompletedNot Applicable

NCT05358132

ARM-ED: Advanced Respiratory Monitoring Events in Drug Toxicity

There is a drug-related death crisis in Scotland. The majority of these deaths have involved the misuse of opiates (e.g. heroin) and benzodiazepines (e.g. valiu…

United Kingdom78 participantsStarted 2022-06-08

Treatment: Pneumowave Device placement and data capture

Opioid Toxicity

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis

All recent trials (7 shown)

Pupillary Unrest as an Indicator of Central Opioid Effect in Subjects 40-60 Years of Age

ARM-ED: Advanced Respiratory Monitoring Events in Drug Toxicity

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis

All recent trials (7 shown)

Pupillary Unrest as an Indicator of Central Opioid Effect in Subjects 40-60 Years of Age

ARM-ED: Advanced Respiratory Monitoring Events in Drug Toxicity

Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery

Respiratory Control and Narcotic Effects

Opioid Growth Factor (OGF) and Gemcitabine: Novel Treatment for Pancreatic Cancer

KCNH2 Polymorphisms on the QTc Interval in Kelantanese Malays Patients Receiving Methadone Maintenance Therapy (MMT)