Opioid Substitution Treatment

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Opioid Substitution Treatment trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

RecruitingNot Applicable

NCT05336188

Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder

The proposed clinical trial would evaluate the use of smartphone applications ("apps", which have well-established efficacy in reducing cigarette and alcohol us…

United States255 participantsStarted 2023-05-16

Treatment: Smartphone

RecruitingNot Applicable

NCT06747871

Opioids, Low Nicotine Cigarettes, and Chronic Pain

The purpose of this study is to evaluate the effects of switching to very low nicotine content (VLNC) cigarettes versus normal nicotine content (NNC) cigarettes…

United States60 participantsStarted 2025-04-15

Treatment: Very Low Nicotine Cigarettes (VLNC), Normal Nicotine Cigarettes (NNC)

RecruitingPhase 4

NCT07160075

HIV Prevention With PrEP Among People on Opioid Replacement Therapy

The purpose of this study is to assess the feasibility and acceptability of providing oral pre-exposure prophylaxis (PrEP) and opioid agonist therapy (OAT) simu…

Canada350 participantsStarted 2025-08-28

Treatment: Simultaneous administration of OAT and oral PrEP at existing pharmacy-based programs

RecruitingNot Applicable

NCT05226624

The Alberta Neonatal Abstinence Syndrome Mother-Baby Care ImprovEmeNT Program

Neonatal Abstinence Syndrome (NAS), is a common and costly problem in Alberta that affects approximately 250 babies per year exposed to drugs during pregnancy.…

Canada240 participantsStarted 2023-10-01

Treatment: Rooming-in care, Baseline standard of care

All recent trials (74 shown)

Active — Not RecruitingNot Applicable

NCT05657106

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

This study will test the effectiveness, implementation outcomes, and cost effectiveness of a community-tailored, harm reduction kiosk in reducing HIV, hepatitis…

United States752 participantsStarted 2023-03-06

Treatment: Harm reduction kiosk

CompletedNot Applicable

NCT03221309

Hepatitis C Treatment to Prevent HIV, Initiate Opioid Substitution Therapy, and Reduce Risky Behavior

This is an open label, non-randomized, observational pilot study to evaluate a model of care for treatment of hepatitis C in people with ongoing injection drug…

United States198 participantsStarted 2017-05-01

Treatment: Evaluate model of care for HCV-infected adults with on-going opioid misuse

Opioid Substitution Treatment

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder

Opioids, Low Nicotine Cigarettes, and Chronic Pain

HIV Prevention With PrEP Among People on Opioid Replacement Therapy

The Alberta Neonatal Abstinence Syndrome Mother-Baby Care ImprovEmeNT Program

All recent trials (74 shown)

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

Hepatitis C Treatment to Prevent HIV, Initiate Opioid Substitution Therapy, and Reduce Risky Behavior

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder

Opioids, Low Nicotine Cigarettes, and Chronic Pain

HIV Prevention With PrEP Among People on Opioid Replacement Therapy

The Alberta Neonatal Abstinence Syndrome Mother-Baby Care ImprovEmeNT Program

All recent trials (74 shown)

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

Hepatitis C Treatment to Prevent HIV, Initiate Opioid Substitution Therapy, and Reduce Risky Behavior

A Chatbot To Support Substance Use Recovery

Integrated Treatment of Hepatitis C Virus Infection

Effect of Fruit Smoothie Supplementation on Psychological Distress Among People Receiving Opioid Agonist Therapy

Pilot Study of Methadone Patient Access to Collaborative Treatment: a HEAL Initiative

Integrated Exercise Program in Opioid Agonist Therapy Clinics

Physical Activity as Adjunct Treatment for Opioid Substitution Therapy

ICE-T Pain Regimen for Total Laparoscopic Hysterectomy

The Norwegian Addiction, Pain and Trauma Study

Use of a GLP-1R Agonist to Treat Opioid Use Disorder

Effectiveness of a Training Program for Self-management of the Substance Addiction Consequences - a Study Protocol

Hepatitis C-Video vs. Brochure Education Delivery

Pharmacologically-based Strategies for Opioid Substitution Therapy During Pregnancy

Increasing Linkage to Family Planning Care for Individuals With Substance Use Disorder

Easy Access to Smoking Cessation for People Receiving Opioid Agonist Therapy Who Are Smoking Tobacco

Impact of Pregnancy on Buprenorphine Pharmacokinetics and Pharmacodynamics

MOms in REcovery (MORE) Study: Defining Optimal Care

ETHOS ENGAGE: Enhancing Treatment of Hepatitis C in Opioid Substitution Settings

Extended-release Pharmacotherapy for Opioid Use Disorder