Normal Eyes

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Normal Eyes trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 45 trials

RecruitingNot Applicable

NCT02327884

Characterization of Diseases With Salivary Gland Involvement

Background: \- Salivary glands in and around the mouth and throat make saliva. Salivary gland disorders can affect a person s quality of life. Studying people…

United States1,150 participantsStarted 2015-04-03

RecruitingNot Applicable

NCT00005917

Study of Chediak-Higashi Syndrome

Chediak-Higashi syndrome (CHS) is a rare autosomal recessive disorder characterized in its classical form by oculocutaneous albinism, a bleeding diathesis, recu…

United States60 participantsStarted 2002-09-10

RecruitingNot Applicable

NCT07206238

Orbital Vascular Inflammation in Ischemic Optic Neuropathy and Giant Cell Arteritis

Giant cell arteritis (GCA) is an inflammation of the blood vessels. A dangerous complication is sudden vision loss due to insufficient blood supply to the optic…

Denmark122 participantsStarted 2026-01-14

Treatment: Positron Emission Tomography / Magnetic Resonance Imaging

RecruitingPhase 3

NCT07015190

Neoadjuvant Darovasertib in Primary Uveal Melanoma

This is a Phase 3, randomized, multi-center, open-label study of neoadjuvant darovasertib in subjects with primary non-metastatic uveal melanoma (OptimUM-10)

United States520 participantsStarted 2026-01-25

Treatment: Darovasertib, Primary Local Therapy

RecruitingPhase 1

NCT07085676

Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases

A Phase 1 study of HBI0101 BCMA-CART in B-Cell Mediated Autoimmune Rheumatic Diseases. The goal of the study is evaluation of safety and identification of the m…

Israel120 participantsStarted 2024-09-01

Treatment: HBI0101 CART

RecruitingNot Applicable

NCT03003572

Autoreactive Anti-Ro/SSA IgE To Determine Primary SjögRen's Syndrome's Disease Activity

Primary Sjögren's syndrome (pSS) can affect various organs, sometimes leads to life-threatening conditions and is always responsible for a decreased quality of…

France185 participantsStarted 2018-03-27

Treatment: Blood samples

All recent trials (100 shown)

Active — Not RecruitingPhase 3

NCT06741969

Nipocalimab in Moderate to Severe Sjogren's Disease

The purpose of this study is to evaluate the clinical efficacy and safety of nipocalimab in participants with moderate to severe Sjogren's disease (SjD).

United States655 participantsStarted 2024-12-04

Treatment: Nipocalimab, Placebo

TerminatedPhase 2

NCT06312020

A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome

The purpose of this study is to measure the efficacy and safety of HZN-1116 in participants with Sjogren's syndrome (SS).

United States209 participantsStarted 2024-05-09

Treatment: HZN-1116, Placebo

Normal Eyes

Trial phase breakdown

Trial status

Actively recruiting — 45 trials

Characterization of Diseases With Salivary Gland Involvement

Study of Chediak-Higashi Syndrome

Orbital Vascular Inflammation in Ischemic Optic Neuropathy and Giant Cell Arteritis

Neoadjuvant Darovasertib in Primary Uveal Melanoma

Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases

Autoreactive Anti-Ro/SSA IgE To Determine Primary SjögRen's Syndrome's Disease Activity

All recent trials (100 shown)

Nipocalimab in Moderate to Severe Sjogren's Disease

A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome

Trial phase breakdown

Trial status

Actively recruiting — 45 trials

Characterization of Diseases With Salivary Gland Involvement

Study of Chediak-Higashi Syndrome

Orbital Vascular Inflammation in Ischemic Optic Neuropathy and Giant Cell Arteritis

Neoadjuvant Darovasertib in Primary Uveal Melanoma

Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases

Autoreactive Anti-Ro/SSA IgE To Determine Primary SjögRen's Syndrome's Disease Activity

All recent trials (100 shown)

Nipocalimab in Moderate to Severe Sjogren's Disease

A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome

A Single Bolus of Dexmedetomidine Versus Normal Saline in Postoperative Agitation

Analysis of Specimens From Individuals With Pulmonary Fibrosis

Transarterial Chemoembolization for the Treatment of Uveal Melanoma With Liver Metastases

ADX-629 Therapy for Sjogren-Larsson Syndrome

Outcomes From Hyperbaric Oxygen (HBO2) Treatment for Emerging Indications

Wheat-free Diet in the Treatment of Sjogren's Syndrome

Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases

Clinical Trial Evaluating Rituximab in Ocular Cicatricial Pemphigoid

Macular Pigment Measurements in Eye & Other Tissues

Immune Profile of Saliva and Serum of Patients With Primary Sjögren´s Syndrome

Ophthalmological Adverse Events of Tralokinumab in AD

Natural History Study of Patients With Neurofibromatosis Type I

An AI Algorithm for Lymphocyte Focus Score of Minor Salivary Gland Biopsy Samples for Diagnosing Sjogren's Syndrome

A Randomized, Double-blind 2-arm, Followed by an Open-label 1-arm, NEPTUNUS Extension Study to Assess the Long-term Safe…

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Uveitis/Intraocular Inflammatory Disease Biobank (iBank)

Outcomes of CTAK Surgery

Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.