RecruitingPhase 3
NCT04853342To Assess the Efficacy and Safety of Furmonertinib Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mut…
This is a phase 3 double-blind, randomized, placebo-controlled, study to assess the efficacy and safety of Furmonertinib (AST2818) versus placebo in patients wi…
China318 participantsStarted 2021-06-07Updated 2026-08-13 Treatment: Drug: Furmonertinib 80 mg, Furmonertinib 80 mg placebo
RecruitingPhase 3
NCT06970639A Study Evaluating Furmonertinib Plus Platinum-based Doublet Chemotherapy Versus Osimertinib in Patients With Epidermal…
This study is a Phase III, international, multicenter, randomized, controlled, open-label clinical trial. The primary objective is to evaluate the efficacy and…
China380 participantsStarted 2024-09-26Updated 2026-08-13 Treatment: Furmonertinib Mesilate Tablets, Carboplatin Injection
RecruitingPhase 3
NCT07185997Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Li…
Global, Phase 3, randomized, multicenter, open-label study evaluating the efficacy and safety of firmonertinib at a dose level of 240 mg QD compared to investig…
United States, Australia +14 more480 participantsStarted 2025-12-17Updated 2026-08-03 Treatment: Firmonertinib, EGFR-TKI inhibitor based on investigator's choice