Microsatellite Unstable Colorectal Cancer

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Microsatellite Unstable Colorectal Cancer trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

All recent trials (3 shown)

By InvitationPhase 2

NCT07542262

Low-dose Immunotherapy in Metastatic and Locally Advanced Colorectal and Gastric MSI/dMMR Cancers

It is planned to study the effectiveness of low-dose immunotherapy (IT) nivolumab 40 mg for either 2 courses of therapy or 6 courses as preoperative therapy in…

Russia128 participantsStarted 2025-06-03

Treatment: Low-dose nivolumab, Low-dose nivolumab with/without chemotherapy

CompletedPhase 2

NCT02060188

A Study of Nivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has Spread

The purpose of this study is to examine if Nivolumab by itself, or Nivolumab in combination with other anti-cancer drugs, will result in meaningful tumor size r…

United States385 participantsStarted 2014-03-12

Treatment: Ipilimumab, Nivolumab

CompletedPhase 2

NCT01876511

Study of MK-3475 in Patients With Microsatellite Unstable (MSI) Tumors (Cohorts A, B and C)

This study will be looking at whether MK-3475 (an antibody that blocks negative signals to T cells) is effective (anti-tumor activity) and safe in three differe…

United States113 participantsStarted 2013-09

Treatment: MK-3475