Maxillofacial Abnormalities

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Maxillofacial Abnormalities trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 30 trials

RecruitingNot Applicable

NCT06315348

Effect on Periodontal Phenotype of Flapless Piezoincission During Orthodontic Treatment

Research Question While the reduction in treatment times and the patient satisfaction after periodontally accelerated osteogenic orthodontics (PAOO) are well s…

Spain40 participantsStarted 2024-04-20

Treatment: flapless alveolar decortication with augmentation

RecruitingNot Applicable

NCT01630447

Genetic and Functional Analysis of Cherubism

The goal of this research study is to identify genes and regulatory elements on chromosomes that cause cherubism. Together with the investigators collaborators…

United States600 participantsStarted 2009-04

RecruitingPhase 4

NCT06962306

Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following…

United States60 participantsStarted 2025-06-04

Treatment: Methadone hydrochloride, Fentanyl/Hydromorphone

RecruitingNot Applicable

NCT07301918

Leaf Expander Versus Hyrax Expander in Mixed Dentition Patients With Posterior Crossbite.

Design: Two-arm parallel randomized clinical trial in mixed dentition (6-12 years). Arms: (1) 9 mm, 900 g leaf expander; (2) 9 mm Hyrax expander. Follow-up: Fr…

Egypt30 participantsStarted 2025-10-01

Treatment: The Leaf expander, Hyrax expander

RecruitingNot Applicable

NCT04190953

Upper Airway's Pressure Drop Analyses After Mandibular Advancement and Maxillary Expansion

Breathing is a crucial function for everyone. Breathing impairment in children could lead to behavioral and cognitive problems at least. But what if orthodontic…

Canada90 participantsStarted 2020-02-18

Treatment: Twin block then Hyrax, Hyrax then Twin block

RecruitingNot Applicable

NCT02639312

Natural History of Craniofacial Anomalies and Developmental Growth Variants

Background: Some head and facial abnormalities are rare and present at birth. Others are more common, and may not show up until puberty. These conditions have…

United States2,400 participantsStarted 2016-04-18

All recent trials (100 shown)

CompletedNot Applicable

NCT05331456

Alveolar Cleft Repair Using Osteoinductive Ceramics

In this study, patients with unilateral cleft lip and palate are enrolled in a multicenter stepped wedge randomized trial ithat compares alveolar cleft closure…

Netherlands84 participantsStarted 2022-06-01

Treatment: Unilateral alveolar cleft repair

CompletedNot Applicable

NCT00001721

Study of Smith-Lemli-Opitz Syndrome

Smith-Lemli-Opitz Syndrome (SLOS) is a genetic disorder (autosomal recessive) caused by an abnormality in the production of cholesterol. The disorder can occur…

United States130 participantsStarted 1998-09-13

Treatment: Cholesterol Suspension, CRH

Maxillofacial Abnormalities

Trial phase breakdown

Trial status

Actively recruiting — 30 trials

Effect on Periodontal Phenotype of Flapless Piezoincission During Orthodontic Treatment

Genetic and Functional Analysis of Cherubism

Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

Leaf Expander Versus Hyrax Expander in Mixed Dentition Patients With Posterior Crossbite.

Upper Airway's Pressure Drop Analyses After Mandibular Advancement and Maxillary Expansion

Natural History of Craniofacial Anomalies and Developmental Growth Variants

All recent trials (100 shown)

Alveolar Cleft Repair Using Osteoinductive Ceramics

Study of Smith-Lemli-Opitz Syndrome

Trial phase breakdown

Trial status

Actively recruiting — 30 trials

Effect on Periodontal Phenotype of Flapless Piezoincission During Orthodontic Treatment

Genetic and Functional Analysis of Cherubism

Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

Leaf Expander Versus Hyrax Expander in Mixed Dentition Patients With Posterior Crossbite.

Upper Airway's Pressure Drop Analyses After Mandibular Advancement and Maxillary Expansion

Natural History of Craniofacial Anomalies and Developmental Growth Variants

All recent trials (100 shown)

Alveolar Cleft Repair Using Osteoinductive Ceramics

Study of Smith-Lemli-Opitz Syndrome

A Single Bolus of Dexmedetomidine Versus Normal Saline in Postoperative Agitation

Research on Deep Learning-Based Intelligent Diagnosis and Treatment

a Comparative Analysis of Subspinal and Conventional Le Fort I Osteotomy on Nasolabial Soft Tissues

Facial iD Customized Mandible Reconstruction Plates

Preventive EXACYL® on Perioperative Bleeding During Orthognathism of Maxillary Surgery

MRI Assessment of Velopharyngeal Anatomy After Modified Furlow-Buccinator Flap in Late Primary Palate Repair

Effects of Local Ketamine in Orthognathic Procedures

Assessment of the Influence of Cleft Repair on Microcirculation of the Palate

Evaluation of Emotional Responses Using the I-Motions System and Self-assessment Questionnaires, and Assessment of Posto…

3D-Printed Patient-Specific Surgical Plates Versus Conventional Surgical Plates in Jaw Reconstruction

Speech Intervention Via Telepractice for Children With Repaired Cleft Palate

Three Dimensional Evaluation of Dento-Skeletal Effects of Leaf Self Expander in Cleft Lip and Palate Patients

Maxillary Patient Specific Implants in Bimaxillary Orthognathic Surgery

Evaluation of Trigeminal Nerve Blockade

Study Evaluating the Performance and Safety of Global D Implants Indicated for Orthognathic Surgery

Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet)

Repair of Oronasal Fistula Using Interpositional Buccal Pad of Fat as a Free Graft in a Cleft Palate Patient

Comparison of Skeletal Anchorage Versus Conventional Tooth-Borne Face Mask Therapy Following the Alt-RAMEC Protocol