Liver Regeneration

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Liver Regeneration trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

RecruitingNot Applicable

NCT07142213

Effect and Mechanism of ALPPS Operation on Liver Regeneration

Hepatobiliary malignancies-principally hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA)-are highly aggressive and often diagnosed at advanced stages.…

China50 participantsStarted 2020-01-01

Treatment: ALPPS

RecruitingNot Applicable

NCT07085806

To Study Effect of Injection Pentoxifylline on Liver Growth After Major Liver Surgery

Posthepatectomy liver failure (PHLF) remains a significant life-threatening problem after major hepatectomies. Pentoxifylline is shown to have potent vasodilati…

India60 participantsStarted 2025-01-01

Treatment: Pentoxifylline (also known as oxpentifylline), Plasmalyte

RecruitingNot Applicable

NCT06681818

Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

the investigators will pursue two specific aims: (1) to monitor the extent of heme oxygenase induction (by measuring endogenous CO production) in relationship t…

United States125 participantsStarted 2025-11-21

Treatment: carbon monoxide measurement via smokerlyzer

RecruitingNot Applicable

NCT06914648

The Dragon PLC Trial (DRAGON-PLC)

The goal of the DRAGON PLC clinical trial is to determine whether portal vein embolization (PVE) combined with hepatic vein embolization (HVE) improves resectab…

United States358 participantsStarted 2025-04-01

Treatment: Portal Vein Embolization, Hepatic Vein Embolization

RecruitingNot Applicable

NCT06126419

Application of High-dose Insulin Therapy to Improve Liver Function and Regeneration

The primary objective of this interventional study is determine if the future liver remnant can be optimized by improving liver function pre-operatively in pati…

Canada70 participantsStarted 2023-11-08

Treatment: High-Dose Insulin Therapy

All recent trials (50 shown)

By InvitationNot Applicable

NCT07329296

The Regenerative Capacity of the Donor Liver After Living Donor Liver Transplantation: an Ambidirectional Cohort Study

Rationale: Living donor liver transplantation (LDLT) offers a promising solution to the organ shortage. During living liver donation, a substantial portion of t…

Netherlands90 participantsStarted 2026-02-01

Treatment: Living liver donation

Not Yet RecruitingNot Applicable

NCT07300709

Renal Histopathology and Transcriptomic Analysis in Hepatorenal Syndrome During Liver Transplantation

Hepatorenal Syndrome (HRS) is a serious complication that can occur in patients with liver cirrhosis, characterised by kidney dysfunction, or acute kidney failu…

Hong Kong42 participantsStarted 2026-01-01

Treatment: renal biopsy

Liver Regeneration

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Effect and Mechanism of ALPPS Operation on Liver Regeneration

To Study Effect of Injection Pentoxifylline on Liver Growth After Major Liver Surgery

Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

The Dragon PLC Trial (DRAGON-PLC)

Application of High-dose Insulin Therapy to Improve Liver Function and Regeneration

All recent trials (50 shown)

The Regenerative Capacity of the Donor Liver After Living Donor Liver Transplantation: an Ambidirectional Cohort Study

Renal Histopathology and Transcriptomic Analysis in Hepatorenal Syndrome During Liver Transplantation

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Effect and Mechanism of ALPPS Operation on Liver Regeneration

To Study Effect of Injection Pentoxifylline on Liver Growth After Major Liver Surgery

Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

The Dragon PLC Trial (DRAGON-PLC)

Application of High-dose Insulin Therapy to Improve Liver Function and Regeneration

All recent trials (50 shown)

The Regenerative Capacity of the Donor Liver After Living Donor Liver Transplantation: an Ambidirectional Cohort Study

Renal Histopathology and Transcriptomic Analysis in Hepatorenal Syndrome During Liver Transplantation

Effect of Ursodeoxycholic Acid Supplementation on Liver Regeneration on Right Lobe Donor Hepatectomy

National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Evaluating Mesenchymal Stem Cell Therapy in N…

A Machine Learning Architecture to Predict Post-Hepatectomy Liver Failure Using Liver Regeneration Biomarkers and Time-P…

Simultaneous Portal and Hepatic Vein Versus Portal Vein Embolizations for Hypertrophy of the Future Liver Remnant

Safety and Feasibility of Human Umbilical Cord Mesenchymal Stem Cell-Derived Secretome in the Treatment of Liver Cirrhos…

Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration a…

Reversible Portal Vein Embolization Before Major Hepatectomy

Effect of Novel Donor Lifestyle Optimisation Protocol on Liver Regeneration in Live Liver Donors

Granulocyte Colony Stimulating Factor Four Week Plus N-Acetyl Cysteine in Severe Alcoholic Hepatitis

Effect of BCAA Supplementation on Muscle Mass, Muscle Quality and Molecular Markers of Muscle Regeneration in CLD Patien…

Splenic Artery Ligation and Portocaval Shunt in Small-for-size Syndrome

Polydeoxyribonucleotide (PDRN) for Cuff Regeneration

Liver Regeneration

Randomized Controlled Trial to Study the Outcome of Intravenous Phosphate Supplementation in Live Donors Undergoing Hepa…

Administration of Rifaximin to Improve Liver Regeneration and Outcome Following Major Liver Resection

Study of Mediators of Post Hepatectomy Liver Regeneration

HEpatic Regeneration With COupled Plasma Filtration and Adsorption for Liver Extracorporeal Detoxification

ARAPS Study on Accelerated Liver Regeneration