Leukocyte-Adhesion Deficiency Syndrome

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Leukocyte-Adhesion Deficiency Syndrome trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

RecruitingNot Applicable

NCT00128973

Evaluation of Patients With Immune Function Abnormalities

This study will evaluate patients with abnormal immune function that results in recurrent or unusual infections or chronic inflammation. This may include inheri…

United States3,500 participantsStarted 2005-09-19

RecruitingNot Applicable

NCT04528355

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

This is a data collection study that will examine the general diagnostic and treatment data associated with the reduced-intensity chemotherapy-based regimen pai…

United States50 participantsStarted 2020-08-20

Treatment: data collection

RecruitingPhase 2

NCT01962415

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

The objective of this study is to evaluate the efficacy of using a reduced-intensity condition (RIC) regimen with umbilical cord blood transplant (UCBT), double…

United States100 participantsStarted 2014-02-04

Treatment: Hydroxyurea, Alemtuzumab

All recent trials (12 shown)

CompletedPhase 2

NCT01998633

Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204)

HLH, HLH-related disorders, Chronic Granulomatous (CGD), HIGM1, Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX) and sever…

United States47 participantsStarted 2013-12

Treatment: Hematopoietic Stem Cell Transplant

CompletedPhase 1

NCT01917708

Bone Marrow Transplant With Abatacept for Non-Malignant Diseases

This is a single arm, phase I study to assess the tolerability of abatacept when combined with cyclosporine and mycophenolate mofetil as graft versus host disea…

United States10 participantsStarted 2014-01

Treatment: Abatacept

Leukocyte-Adhesion Deficiency Syndrome

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

Evaluation of Patients With Immune Function Abnormalities

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

All recent trials (12 shown)

Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204)

Bone Marrow Transplant With Abatacept for Non-Malignant Diseases

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

Evaluation of Patients With Immune Function Abnormalities

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

All recent trials (12 shown)

Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204)

Bone Marrow Transplant With Abatacept for Non-Malignant Diseases

Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation

Gene Therapy for Patients With Leukocyte Adherence Deficiency (Follow-Up of Phase 1 Trial)

Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells

Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies

Interferon Gamma to Treat Leukocyte Adhesion Deficiency Type I

Stem Cell Transplantation to Treat Leukocyte Adhesion Deficiency

Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders